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Long-term inhibition of ethanol intake by the administration of an aldehyde dehydrogenase-2 (ALDH2)-coding lentiviral vector into the ventral tegmental area of rats
(Society for the Study of Addiction, 2014)
Previous studies suggest that acetaldehyde generated from ethanol in the brain is reinforcing. The present studies tested
the feasibility of achieving a long-term reduction of chronic and post-deprivation binge ethanol ...
p27Kip1 Knockdown Induces Proliferation in the Organ of Corti in Culture after Efficient shRNA Lentiviral Transduction
(Association for Research in Otolaryngology, 2013)
The cells in the organ of Corti do not exhibit
spontaneous cell regeneration; hair cells that die after
damage are not replaced. Supporting cells can be
induced to transdifferentiate into hair cells, but that
would ...
An Anticatalase Lentiviral Vector Reduced Ethanol Intake in Developmentally-Lead-Exposed Rats
(Oxford Univ Press, 2015)
Gene Therapy Using a Self-Inactivating Lentiviral Vector Improves Clinical and Laboratory Manifestations of Wiskott-Aldrich Syndrome
(American Soc. Hematology, 2015)
The Alcohol Deprivation Effect:Marked Inhibition by Anticatalase Gene Administration into the Ventral Tegmental Area in Rats
(2013)
Background: Animals that have chronically consumed alcohol and are subsequently deprived of it
markedly increase their intake above basal levels when access to alcohol is reinstated. Such an effect,
termed the alcohol ...
Silencing brain catalase expression reduces ethanol intake in developmentally-lead-exposed rats
(Elsevier B.V., 2019)
© 2018 Elsevier B.V. Lead (Pb) is a developmental neurotoxicant. We have demonstrated that perinatally Pb-exposed rats consume more ethanol than their control counterparts, a response that seems to be mediated by catalase ...
SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells
(Spandidos, 2016)
The incidence and mortality rates of prostate cancer (PCa) are increasing, and PCa is almost the second-leading cause of cancer-associated mortality in men. During tumor progression, epithelial cells decrease the number ...